Round 4 of the Machineseeker EHF Champions League 2025/26 opened Wednesday night with four commanding victories — each by a margin of at least nine goals. In group A, HBC Nantes stunned Sporting Clube de Portugal 39:28 following a jaw-dropping 23:11 half-time lead, while Aalborg Håndbold downed Kolstad Håndball 35:26 in a Nordic derby. In the early matches in group B, title holders SC Magdeburg defeated GOG 39:30, while Orlen Wisla Plock took a clear 36:25 win against HC Eurofarm Pelister.