The EHF Champions League Women threw off with the Romanian derby in Round 1, leaving CSM Bucuresti disappointed in Bistrița's Teraplast Arena following a massive performance by CS Gloria 2018 BN's goalkeeper Renata De Arruda. FTC-Rail Cargo Hungaria managed to defend their home ground despite good efforts by Nykøbing Falster Håndbold.

The Match of the Week justified its name as Team Esbjerg made a comeback after being down by eight against Györi Audi ETO KC, but still came short in the last moments of the game despite Henny Reistad's 15 goals. Brest Bretagne Handball celebrated their second-ever win against Vipers Kristiansand, while Krim Mercator opened their account with a narrow 24:23 win over Podravka Vegeta.